Until the 18th century, they were subordinate to the kehilla in Tykocin. After the establishment of the kehilla in Nasielsk, all Jews living in the Zakroczym Land were subordinated to it, and in the years 1795-1798 - also those living in Wyszków and the surrounding area. In the 1820s, about 1650-1750 Jews lived in Nasielsk (about 64% of the total population of the town), and the Jewish community, apart from the synagogue, also had a wooden hospital and a wooden school.

In the 18th century, the Jews living in Nasielsk earned their living mainly by renting inns, distilleries and breweries. They also dealt with tailoring, furriery and haberdashing, as evidenced by the establishment in Nasielsk in 1753 of the oldest guild of these craftsmen in Mazovia. The association was autonomous from the city council and had its own synagogue. The town organized eight fairs a year and permanent markets, which favoured the development of trade. In the 1820s, Jews ran a tannery and a cloth factory in Nasielsk. They were also involved in inn-keeping, although this was a reason of conflicts between the Jews and the clergy and private owners of Nasielsk. In the middle of the nineteenth century, the so-called “Jewish rebellion” took place in the town, which was a reaction to the monopolization of vodka production planned by the town's owner, Aleksander Kurtz. In the second half of the 19th century the Jews from Nasielsk were involved in trade on a large scale.

At the turn of the 19th and 20th century, Nasielsk was inhabited by over 4 thousand Jews, who in 1893 constituted over 80% of the inhabitants of the town. In 1880, the 17th-century synagogue was pulled down and replaced by a new, brick building. Shortly afterwards, Abraham Bornstein, the Hasidic leader and founder of the Sochaczew dynasty, became rabbi. In 1900, there were 10 cheders in the town. From the beginning of the 20th century the Jews from Nasielsk started to get involved in the Zionists movement, the Bund and Agudath. The latter opened a girls' school in the interwar period. In the interwar period, poverty prevailed, and 200 families benefited from the support provided by the Jewish aid organization, Joint. In 1939, 3,500 Jews lived in Nasielsk, constituting over 58% of the total population.

During World War II, in December 1939, the Germans deported all Jews from the town. Initially, they were moved to Królewiec, from where they were moved to Międzyrzec Podlaski and Łuków. The Jews from Nasielsk were also sent to e.g. Jadów, Kock and Warsaw. In all these places they met the same tragic fate as local Jewish communities. In the years 1941-1943 in Nasielsk there was a labour camp for Poles and Jews for approx. 150 people.

The Jewish cemetery in Nasielsk was probably built in the second half of the 19th century. It was established on a plot of land located east of the city. The necropolis was devastated during World War II and in the post-war years. Until 2012, there was only one matzevah left in the cemetery, probably from the grave of Awraham Menachem, who died in 1887. The cemetery is now closed.

The Nasielsk Jewish cemetery is located on Kwiatowa Street. Currently, it covers an area of 2 ha. There are no matzevot left in the cemetery. There is a modest information board with the following inscription: “Cemetery of the Jewish community. Financed from the funds of the Act Locally Program”. Next to it there is a plaque which presents the history of the Jewish community of Nasielsk. Moreover, a metal plaque commemorating the local Jewish community was placed under one of the trees of the birch alley running perpendicularly to Kwiatowa Street (with an inscription in English).

Owner of copyrights to the description: POLIN Museum of the History of Polish Jews